One of the ways a genetic trait or disease caused by a mutated (changed) gene on the X chromosome can be passed down (inherited) from parent to child. In X-linked recessive inheritance, a daughter inherits a single mutated gene on the X chromosome from one of her parents. The X chromosome she inherits from the other parent will usually cancel the effect of the mutation, and she most likely will not have the genetic disease. If she inherits a mutated copy of the gene from both parents, she will be affected with the disease. Fathers cannot pass X-linked recessive disease to their sons. When a son inherits a mutated gene on the X chromosome from his mother, the genetic disease is more likely to occur.
A Name That Does Too Much Work
Jean-Martin Charcot's name appears throughout medicine, but nowhere does it create more confusion than in the foot. Learn why the CMT foot and Charcot neuroarthropathy, also known as Charcot foot, share a name yet differ in how they develop, appear, and are managed.
