CMT can also affect areas of the body that are not always included in basic symptom lists. These symptoms are not universal and vary widely from person to person, but they are part of the broader picture of the disease. Some stem directly from nerve involvement, while others develop gradually from changes in strength, posture, balance, or long-term gait patterns.
Musculoskeletal complications can include scoliosis, kyphosis, or a combination of both, known as kyphoscoliosis. Hip dysplasia can occur in some individuals, often in early childhood. Joint instability, altered weight distribution, and chronic muscle imbalance may contribute to these structural changes over time. Contractures of the hands or feet, tremor, and chronic postural strain can also appear as CMT progresses.
CMT can sometimes affect systems beyond movement and sensation. Neurogenic bladder, neurogenic bowel, hearing loss, pupil abnormalities, vestibular problems, and optic nerve atrophy have all been reported. These symptoms are less common, but they illustrate the range of ways CMT can influence peripheral and cranial nerve pathways. Fatigue and chronic pain are also common, and they can significantly shape day-to-day functioning.
These additional symptoms do not appear in everyone who has CMT. They reflect the wide variability of the disease and the many ways peripheral nerves support movement, sensory function, and other body functions. Each person experiences their own mix of symptoms and their own level of symptom severity. One thing is certain: there is no single CMT symptom pattern that applies to everyone.
This is not a complete accounting of CMT symptoms. Not everything someone with CMT experiences is necessarily caused by the disease. It is important to discuss your symptoms with a qualified healthcare provider and follow their guidance.
