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Heterozygous - Charcot-Marie-Tooth Disease | Experts in CMT

Heterozygous

One of Each

Heterozygous (het-er-oh-ZY-gus), as related to genetics, refers to having inherited different versions (alleles) of a genomic marker from each biological parent. Thus, an individual who is heterozygous for a genomic marker has two different versions of that marker. By contrast, an individual who is homozygous has two identical versions. In CMT, a dominant subtype is heterozygous, meaning only one copy of the mutated gene is needed to cause the disease.

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