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Schwann Cells - Charcot-Marie-Tooth Disease | Experts in CMT

Schwann Cells

Myelin’s Makers

Schwann cells (shwahn) are the cells that wrap around the axons of peripheral nerves to form the myelin sheath, the insulation that lets nerve signals travel quickly. Several forms of CMT, including CMT1A and HNPP, arise from mutations that disrupt the instructions Schwann cells use to build peripheral nerve myelin.

The Dorsal Root

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A Name That Does Too Much Work

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When Medicine Lost Its Compass

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Error 404: Gene Not Found

CMT genetic testing often fails to identify the cause of the disease, even when comprehensive panels are used. Here, we discuss why this happens, what genetic tests can and cannot do, and why a negative result still matters.