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Proband - Charcot-Marie-Tooth Disease | Experts in CMT

Proband

Patient Zero

A proband (PROH-band) is the family member through whom a family’s genetic disease first comes to attention, usually the first person diagnosed. Mapping a family around the proband lets clinicians trace how a disease is passing through the generations. In CMT, the proband might be the first relative to receive a diagnosis, even though the disease may have been present in the family for generations.

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The Dorsal Root

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Jean-Martin Charcot lecturing at the Salpêtrière while comparing anatomical illustrations of a cavovarus Charcot-Marie-Tooth (CMT) foot and a Charcot neuroarthropathy foot, highlighting two different conditions that share the Charcot name.


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When Medicine Lost Its Compass

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Error 404: Gene Not Found

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