A proband (PROH-band) is the family member through whom a family’s genetic disease first comes to attention, usually the first person diagnosed. Mapping a family around the proband lets clinicians trace how a disease is passing through the generations. In CMT, the proband might be the first relative to receive a diagnosis, even though the disease may have been present in the family for generations.
A Name That Does Too Much Work
Jean-Martin Charcot's name appears throughout medicine, but nowhere does it create more confusion than in the foot. Learn why the CMT foot and Charcot neuroarthropathy, also known as Charcot foot, share a name yet differ in how they develop, appear, and are managed.
